Effects of intense exercise in chronic spinal cord injury
Background: Exercise has beneficial effects on muscle and motor function after spinal cord injury (SCI). Little is known regarding effects of prolonged intense exercise (IE) in humans with chronic SCI. Design: Prospective, non-randomized, controlled observational study. The intervention was either a...
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Veröffentlicht in: | Spinal cord 2008-11, Vol.46 (11), p.733-737 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background:
Exercise has beneficial effects on muscle and motor function after spinal cord injury (SCI). Little is known regarding effects of prolonged intense exercise (IE) in humans with chronic SCI.
Design:
Prospective, non-randomized, controlled observational study. The intervention was either a multimodal IE program (
n
=21) or a control (CTL) intervention consisting of self-regulated exercise (
n
=8).
Objective:
Measure sensorimotor function over 6 months in relation to an IE program.
Setting:
Single outpatient center.
Subjects:
Subjects with chronic SCI (
n
=29 total), mainly ASIA Impairment Scale A and B, injury levels C4-T11.
Results:
Baseline neurological assessments (for example, ASIA motor score, 39±3 vs 42±5, IE vs CTL,
P
>0.5, mean±s.e.m.) did not differ between the two groups. During the 6 months, IE subjects averaged 7.3±0.7 h per week exercise, not significantly different from CTL subjects (5.2±1.3 h per week,
P
>0.1). However, after 6 months, IE subjects showed significantly greater motor gains than CTL subjects in the main outcome measure, ASIA motor score (change of 4.8±1.0 vs −0.1±0.5 points,
P
=0.0001). The main outcome measure was calculated by ASIA motor score. These IE subject ASIA motor gains correlated with number of exercise hours per week (
r
=0.53,
P |
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ISSN: | 1362-4393 1476-5624 |
DOI: | 10.1038/sc.2008.56 |