Galectin-3 – A jack-of-all-trades in cancer
Highlights ► Galectin-3 has multiple inter- and sub-cellular localizations. ► Alterations of galectin-3 expression and localization are common in cancer. ► Galectin-3 regulates cancer development, progression and metastasis. ► Galectin-3 interacts with different ligands at different localizations....
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Veröffentlicht in: | Cancer letters 2011-12, Vol.313 (2), p.123-128 |
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container_title | Cancer letters |
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creator | Newlaczyl, Anna U Yu, Lu-Gang |
description | Highlights ► Galectin-3 has multiple inter- and sub-cellular localizations. ► Alterations of galectin-3 expression and localization are common in cancer. ► Galectin-3 regulates cancer development, progression and metastasis. ► Galectin-3 interacts with different ligands at different localizations. |
doi_str_mv | 10.1016/j.canlet.2011.09.003 |
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subjects | adhesion angiogenesis Apoptosis Apoptosis - physiology Breast cancer Cancer adhesion Carbohydrates carcinogenesis Cell adhesion & migration Cell Adhesion - physiology Cell growth Cytoplasm Endothelium Galectin 3 - chemistry Galectin 3 - metabolism Galectin-3 Gene expression Hematology, Oncology and Palliative Medicine Humans Ligands Medical prognosis Medical research Metastasis Neoplasm Invasiveness Neoplasm Metastasis Neoplasms - metabolism Neoplasms - pathology Neovascularization, Pathologic - metabolism Progression Proteins |
title | Galectin-3 – A jack-of-all-trades in cancer |
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