Autophagic Factors Cut to the Bone
Autophagy is an intracellular membrane-trafficking pathway for the delivery of proteins and organelles to lysosomes for degradation and recycling. DeSelm and coworkers (2011) now describe an essential role for autophagic proteins in the trafficking and fusion of lysosomes at the site of bone resorpt...
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| Veröffentlicht in: | Developmental cell 2011-11, Vol.21 (5), p.808-810 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Autophagy is an intracellular membrane-trafficking pathway for the delivery of proteins and organelles to lysosomes for degradation and recycling. DeSelm and coworkers (2011) now describe an essential role for autophagic proteins in the trafficking and fusion of lysosomes at the site of bone resorption: the osteoclast ruffled border. |
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| ISSN: | 1534-5807 1878-1551 |
| DOI: | 10.1016/j.devcel.2011.10.021 |