17-alphahydroxyprogesterone caproate in women with previous spontaneous preterm delivery: does a previous term delivery affect the rate of recurrence?

17-alphahydroxyprogesterone caproate in women with previous spontaneous preterm delivery: does a previous term delivery affect the rate of recurrence?

Objective The purpose of this study was to determine the role of previous term delivery on the rate of recurrent preterm birth in women with previous spontaneous preterm delivery (SPTD) who receive 17-alphahydroxyprogesterone caproate (17P) therapy. Study Design Women with singleton gestations who w...

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Veröffentlicht in:American journal of obstetrics and gynecology 2011-09, Vol.205 (3), p.269.e1-269.e6
Hauptverfasser: Barton, John R., MD, Barton, Lucy A., BS, Istwan, Niki B., RN, Rhea, Debbie J., MPH, Desch, Cheryl N., MS, Sibai, Baha M., MD
Format: Artikel
Sprache:eng
Schlagworte:
17-alphahydroxyprogesterone caproate prophylaxis
Adult
Biological and medical sciences
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Hydroxyprogesterones - therapeutic use
Infant, Newborn
Infant, Premature
Medical sciences
Obstetrics and Gynecology
Pregnancy
Pregnancy. Fetus. Placenta
Premature Birth - prevention & control
preterm delivery
Progestins - therapeutic use
recurrent preterm delivery
Retrospective Studies
Risk
Secondary Prevention
Term Birth
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Zusammenfassung:Objective The purpose of this study was to determine the role of previous term delivery on the rate of recurrent preterm birth in women with previous spontaneous preterm delivery (SPTD) who receive 17-alphahydroxyprogesterone caproate (17P) therapy. Study Design Women with singleton gestations who were receiving 17P therapy were studied. Rates of recurrent SPTD were compared for 1 or ≥2 SPTD with and without a previous term delivery. Results Five thousand one hundred two women had 1 previous SPTD, and 2217 women had ≥2 SPTDs. In women with 1 previous SPTD, a previous term delivery had lower rates of SPTD at
ISSN:0002-9378
1097-6868
DOI:10.1016/j.ajog.2011.06.039