Efficacy of dual vaccination of pandemic H1N1 2009 influenza and seasonal influenza on institutionalized elderly: A one-year prospective cohort study

Highlights ► Dual vaccination of seasonal influenza and H1N1 2009 in institutionalized elderly. ► Functional status and comorbidity assessed to minimize healthy vaccine bias. ► Dual vaccination was better than vaccination of seasonal influenza alone. ► Reduce all cause mortality and hospitalization...

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Veröffentlicht in:	Vaccine 2011-10, Vol.29 (44), p.7773-7778
Hauptverfasser:	Chan, T.C, Hung, I.F.N, Luk, J.K.H, Shea, Y.F, Chan, F.H.W, Woo, P.C.Y, Chu, L.W
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Allergy and Immunology Applied microbiology Biological and medical sciences Cohort Studies confidence interval Efficacy elderly Female females fever Fundamental and applied biological sciences. Psychology Hong Kong Hospitalization Hospitalization - statistics & numerical data Hospitals Humans Influenza Influenza A (H1N1) 2009 Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Influenza, Human - mortality Influenza, Human - prevention & control Institutionalization Institutionalized elderly Male Microbiology Miscellaneous Mortality multivariate analysis nursing homes Older people pandemic people pneumonia Prospective Studies Survival Analysis Treatment Outcome Vaccination Vaccination - methods Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Virology World Health Organization
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Zusammenfassung:	Highlights ► Dual vaccination of seasonal influenza and H1N1 2009 in institutionalized elderly. ► Functional status and comorbidity assessed to minimize healthy vaccine bias. ► Dual vaccination was better than vaccination of seasonal influenza alone. ► Reduce all cause mortality and hospitalization by dual vaccination.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2011.07.112