The adrenal peripheral clock: Glucocorticoid and the circadian timing system

Highlights ► Circadian rhythm of glucocorticoid (GC) is tightly regulated by coincident multiple mechanisms. ► Adrenal local clock regulates periodic steroidogenesis and responsiveness of adrenal GC to ACTH. ► Adrenal clock links the central clock and peripheral clocks in the organization of the clo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Frontiers in neuroendocrinology 2011-10, Vol.32 (4), p.451-465
Hauptverfasser:	Son, Gi Hoon, Chung, Sooyoung, Kim, Kyungjin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal gland Adrenal Glands - metabolism Adrenal Glands - physiology Animals Biological clock Biological Clocks - genetics Biological Clocks - physiology Circadian Clocks - genetics Circadian Clocks - physiology Circadian rhythm Endocrinology & Metabolism Glucocorticoid Glucocorticoids - genetics Glucocorticoids - metabolism Glucocorticoids - physiology Glucocorticoids - secretion Humans Hypothalamus–pituitary–adrenal (HPA) axis Models, Biological Neuroendocrine Cells - metabolism Neuroendocrine Cells - physiology Signal Transduction Steroidogenic acute regulatory protein (StAR)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights ► Circadian rhythm of glucocorticoid (GC) is tightly regulated by coincident multiple mechanisms. ► Adrenal local clock regulates periodic steroidogenesis and responsiveness of adrenal GC to ACTH. ► Adrenal clock links the central clock and peripheral clocks in the organization of the clock system. ► Adrenal rhythm have an important role in harmonizing circadian physiology and behavior.
ISSN:	0091-3022 1095-6808
DOI:	10.1016/j.yfrne.2011.07.003