Low incidence of renal impairment observed in tenofovir-treated patients

To compare the incidence of renal impairment in HIV-infected patients exposed versus unexposed to tenofovir and to characterize risk factors associated with renal impairment. We undertook a retrospective cohort and nested case-control study of 514 Northwestern University HIV Outpatient Study partici...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2011-05, Vol.66 (5), p.1120-1126
Hauptverfasser:	O'DONNELL, E. Paul, SCARSI, Kimberly K, DARIN, Kristin M, GERZENSHTEIN, Lana, POSTELNICK, Michael J, PALELLA, Frank J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - administration & dosage Adenine - adverse effects Adenine - analogs & derivatives Adult Aged Anti-HIV Agents - administration & dosage Anti-HIV Agents - adverse effects Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral drugs Antiretroviral Therapy, Highly Active - adverse effects Antiretroviral Therapy, Highly Active - methods Biological and medical sciences Case-Control Studies Chemotherapy Cohort Studies Female HIV HIV Infections - drug therapy Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Incidence Infectious diseases Kidney diseases Male Medical sciences Middle Aged Multivariate analysis Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Organophosphonates - administration & dosage Organophosphonates - adverse effects Pharmacology. Drug treatments Renal failure Renal Insufficiency - chemically induced Retrospective Studies Risk Factors Tenofovir Toxicity Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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