Pegylated interferon–induced immune‐mediated hepatitis post–liver transplantation

A 55‐year‐old Caucasian male developed a well characterized autoimmune hepatitis after completing treatment with pegylated interferon and ribavirin for recurrent hepatitis C. We hypothesize that pegylated interferon triggered a severe form of immune‐mediated hepatitis.

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Bibliographische Detailangaben
Veröffentlicht in:	Liver transplantation 2006-05, Vol.12 (5), p.827-830
Hauptverfasser:	Kontorinis, Nickolas, Agarwal, Kaushik, Elhajj, Nassim, Fiel, M. Isabel, Schiano, Thomas D.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha -Interferon Antiviral Agents - adverse effects Hepatitis C Hepatitis C - complications Hepatitis C - drug therapy Hepatitis, Autoimmune - etiology Humans Interferon Interferon-alpha - adverse effects Liver Cirrhosis - surgery Liver Transplantation - adverse effects Male Middle Aged Polyethylene Glycols - adverse effects Recombinant Proteins Ribavirin
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Beschreibung
Zusammenfassung:	A 55‐year‐old Caucasian male developed a well characterized autoimmune hepatitis after completing treatment with pegylated interferon and ribavirin for recurrent hepatitis C. We hypothesize that pegylated interferon triggered a severe form of immune‐mediated hepatitis.
ISSN:	1527-6465 1527-6473
DOI:	10.1002/lt.20706