Treatment results of bisphosphonate-related osteonecrosis of the jaws
Background. Osteonecrosis of the jaws occurs after the administration of bisphosphonates. An unequivocal treatment strategy is yet to be devised. We assess the treatment of patients with bisphosphonate‐related osteonecrosis of the jaws (BRONJ). Methods. The investigators studied a prospective cohort...
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Veröffentlicht in: | Head & neck 2008-09, Vol.30 (9), p.1224-1230 |
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Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background.
Osteonecrosis of the jaws occurs after the administration of bisphosphonates. An unequivocal treatment strategy is yet to be devised. We assess the treatment of patients with bisphosphonate‐related osteonecrosis of the jaws (BRONJ).
Methods.
The investigators studied a prospective cohort of 58 patients 6 months after surgical treatment of BRONJ. Outcome variables were the status of the mucosa, the visual analog score of pain, and prosthetic rehabilitation. Preoperative staging results were compared with the postoperative outcome and statistically evaluated.
Results.
Of 58 patients, 41 surgically treated patients could be followed up after a mean period of 189 (±23) days. Twenty‐four (58.5%) were free of pain and had an intact mucosa. A statistically significant improvement was registered between preoperative and postoperative staging (p |
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ISSN: | 1043-3074 1097-0347 |
DOI: | 10.1002/hed.20864 |