Measuring the multi-scale integration of mechanical forces during morphogenesis
Highlights ► We identify six developmentally-important morphogenetic spatial scales. ► Cell-intrinsic mechanical forces integrate up spatial scales. ► Extrinsic forces elicit passive responses down spatial scales. ► Non-linear cell behaviour can result from cells sensing mechanical cues. ► Automated...
Gespeichert in:
| Veröffentlicht in: | Current opinion in genetics & development 2011-10, Vol.21 (5), p.653-663 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 663 |
|---|---|
| container_issue | 5 |
| container_start_page | 653 |
| container_title | Current opinion in genetics & development |
| container_volume | 21 |
| creator | Blanchard, Guy B Adams, Richard J |
| description | Highlights ► We identify six developmentally-important morphogenetic spatial scales. ► Cell-intrinsic mechanical forces integrate up spatial scales. ► Extrinsic forces elicit passive responses down spatial scales. ► Non-linear cell behaviour can result from cells sensing mechanical cues. ► Automated image analysis methods now allow multi-scale approaches. |
| doi_str_mv | 10.1016/j.gde.2011.08.008 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_901641910</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0959437X11001316</els_id><sourcerecordid>901641910</sourcerecordid><originalsourceid>FETCH-LOGICAL-c407t-38148249159cbd56126894737d517d91adecf013a35ee6f4a8d18889993828083</originalsourceid><addsrcrecordid>eNp9kU1P3DAQhi0E6i60P4BLlRunhJk4H7aQkCrUFqRFHGil3iyvPdn1Nom3dlKJf0-WXThw4DSHed9HmmcYO0fIELC63GQrS1kOiBmIDEAcsTmKWqbABRyzOchSpgWv_8zYaYwbAMgRq09slqPkwGucs4d70nEMrl8lw5qSbmwHl0ajW0pcP9Aq6MH5PvFN0pFZ695Nq6TxwVBM7L7X-bBd-xX1FF38zE4a3Ub6cphn7PeP779ubtPFw8-7m2-L1BRQDykXWIi8kFhKs7RlhXklZFHz2pZYW4nakmkAueYlUdUUWlgUQkgpucgFCH7GLvbcbfD_RoqD6lw01La6Jz9GJSc_BUqEKYn7pAk-xkCN2gbX6fCkENROo9qoSaPaaVQgFLzQvx7o47Ij-9Z49TYFrvYBmm787yioaBz1hqwLZAZlvfsQf_2ubVr3ovYvPVHc-DH0kzyFKuYK1OPuj7s3IsLkBCv-DE_PlvA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>901641910</pqid></control><display><type>article</type><title>Measuring the multi-scale integration of mechanical forces during morphogenesis</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Blanchard, Guy B ; Adams, Richard J</creator><creatorcontrib>Blanchard, Guy B ; Adams, Richard J</creatorcontrib><description>Highlights ► We identify six developmentally-important morphogenetic spatial scales. ► Cell-intrinsic mechanical forces integrate up spatial scales. ► Extrinsic forces elicit passive responses down spatial scales. ► Non-linear cell behaviour can result from cells sensing mechanical cues. ► Automated image analysis methods now allow multi-scale approaches.</description><identifier>ISSN: 0959-437X</identifier><identifier>EISSN: 1879-0380</identifier><identifier>DOI: 10.1016/j.gde.2011.08.008</identifier><identifier>PMID: 21930371</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Biophysical Phenomena ; Intracellular Space ; Medical Education ; Morphogenesis ; Nonlinear Dynamics ; Stress, Mechanical</subject><ispartof>Current opinion in genetics & development, 2011-10, Vol.21 (5), p.653-663</ispartof><rights>Elsevier Ltd</rights><rights>2011 Elsevier Ltd</rights><rights>Copyright © 2011 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c407t-38148249159cbd56126894737d517d91adecf013a35ee6f4a8d18889993828083</citedby><cites>FETCH-LOGICAL-c407t-38148249159cbd56126894737d517d91adecf013a35ee6f4a8d18889993828083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.gde.2011.08.008$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27926,27927,45997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21930371$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Blanchard, Guy B</creatorcontrib><creatorcontrib>Adams, Richard J</creatorcontrib><title>Measuring the multi-scale integration of mechanical forces during morphogenesis</title><title>Current opinion in genetics & development</title><addtitle>Curr Opin Genet Dev</addtitle><description>Highlights ► We identify six developmentally-important morphogenetic spatial scales. ► Cell-intrinsic mechanical forces integrate up spatial scales. ► Extrinsic forces elicit passive responses down spatial scales. ► Non-linear cell behaviour can result from cells sensing mechanical cues. ► Automated image analysis methods now allow multi-scale approaches.</description><subject>Animals</subject><subject>Biophysical Phenomena</subject><subject>Intracellular Space</subject><subject>Medical Education</subject><subject>Morphogenesis</subject><subject>Nonlinear Dynamics</subject><subject>Stress, Mechanical</subject><issn>0959-437X</issn><issn>1879-0380</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1P3DAQhi0E6i60P4BLlRunhJk4H7aQkCrUFqRFHGil3iyvPdn1Nom3dlKJf0-WXThw4DSHed9HmmcYO0fIELC63GQrS1kOiBmIDEAcsTmKWqbABRyzOchSpgWv_8zYaYwbAMgRq09slqPkwGucs4d70nEMrl8lw5qSbmwHl0ajW0pcP9Aq6MH5PvFN0pFZ695Nq6TxwVBM7L7X-bBd-xX1FF38zE4a3Ub6cphn7PeP779ubtPFw8-7m2-L1BRQDykXWIi8kFhKs7RlhXklZFHz2pZYW4nakmkAueYlUdUUWlgUQkgpucgFCH7GLvbcbfD_RoqD6lw01La6Jz9GJSc_BUqEKYn7pAk-xkCN2gbX6fCkENROo9qoSaPaaVQgFLzQvx7o47Ij-9Z49TYFrvYBmm787yioaBz1hqwLZAZlvfsQf_2ubVr3ovYvPVHc-DH0kzyFKuYK1OPuj7s3IsLkBCv-DE_PlvA</recordid><startdate>20111001</startdate><enddate>20111001</enddate><creator>Blanchard, Guy B</creator><creator>Adams, Richard J</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20111001</creationdate><title>Measuring the multi-scale integration of mechanical forces during morphogenesis</title><author>Blanchard, Guy B ; Adams, Richard J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c407t-38148249159cbd56126894737d517d91adecf013a35ee6f4a8d18889993828083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Animals</topic><topic>Biophysical Phenomena</topic><topic>Intracellular Space</topic><topic>Medical Education</topic><topic>Morphogenesis</topic><topic>Nonlinear Dynamics</topic><topic>Stress, Mechanical</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Blanchard, Guy B</creatorcontrib><creatorcontrib>Adams, Richard J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in genetics & development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Blanchard, Guy B</au><au>Adams, Richard J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Measuring the multi-scale integration of mechanical forces during morphogenesis</atitle><jtitle>Current opinion in genetics & development</jtitle><addtitle>Curr Opin Genet Dev</addtitle><date>2011-10-01</date><risdate>2011</risdate><volume>21</volume><issue>5</issue><spage>653</spage><epage>663</epage><pages>653-663</pages><issn>0959-437X</issn><eissn>1879-0380</eissn><abstract>Highlights ► We identify six developmentally-important morphogenetic spatial scales. ► Cell-intrinsic mechanical forces integrate up spatial scales. ► Extrinsic forces elicit passive responses down spatial scales. ► Non-linear cell behaviour can result from cells sensing mechanical cues. ► Automated image analysis methods now allow multi-scale approaches.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>21930371</pmid><doi>10.1016/j.gde.2011.08.008</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0959-437X |
| ispartof | Current opinion in genetics & development, 2011-10, Vol.21 (5), p.653-663 |
| issn | 0959-437X 1879-0380 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_901641910 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Biophysical Phenomena Intracellular Space Medical Education Morphogenesis Nonlinear Dynamics Stress, Mechanical |
| title | Measuring the multi-scale integration of mechanical forces during morphogenesis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T19%3A41%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Measuring%20the%20multi-scale%20integration%20of%20mechanical%20forces%20during%20morphogenesis&rft.jtitle=Current%20opinion%20in%20genetics%20&%20development&rft.au=Blanchard,%20Guy%20B&rft.date=2011-10-01&rft.volume=21&rft.issue=5&rft.spage=653&rft.epage=663&rft.pages=653-663&rft.issn=0959-437X&rft.eissn=1879-0380&rft_id=info:doi/10.1016/j.gde.2011.08.008&rft_dat=%3Cproquest_cross%3E901641910%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=901641910&rft_id=info:pmid/21930371&rft_els_id=1_s2_0_S0959437X11001316&rfr_iscdi=true |