Epidemiology and treatment of adenoid cystic carcinoma of the minor salivary glands: a meta-analytic study

To evaluate the epidemiological aspects of adenoid cystic carcinoma (ACC) and to evaluate the different therapeutic possibilities as well as the percentage of survival. A retrospective, meta-analytic, observational study was carried out by selecting a total of 13 articles, which provided a sample si...

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Veröffentlicht in:Medicina oral, patología oral y cirugía bucal patología oral y cirugía bucal, 2011-11, Vol.16 (7), p.e884-e889
Hauptverfasser: Martínez-Rodríguez, Natalia, Leco-Berrocal, Isabel, Rubio-Alonso, Luis, Arias-Irimia, Oscar, Martínez-González, José-María
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Sprache:eng
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Zusammenfassung:To evaluate the epidemiological aspects of adenoid cystic carcinoma (ACC) and to evaluate the different therapeutic possibilities as well as the percentage of survival. A retrospective, meta-analytic, observational study was carried out by selecting a total of 13 articles, which provided a sample size of 263 cases of patients who had been diagnosed with ACC in the minor salivary glands. ACC was found to be more common among women (56.5%) and the average age at diagnosis was 55.26 years old. The primary location of the tumor was in the palate in 57% of the cases, the predominant pattern being cribiform. The treatment of choice was therapy combined with surgery and radiotherapy in 62.7% of the subjects. The overall survival rate was 70.76% and 56.76%, at 5 and 10 years respectively. Early detection of adenoid cystic carcinoma is necessary in order to enable making an earlier prognosis and thus enable a better quality of life for the patient.
ISSN:1698-6946
1698-6946
DOI:10.4317/medoral.17200