Psychotripine: A New Trimeric Pyrroloindoline Derivative from Psychotria pilifera

Psychotripine: A New Trimeric Pyrroloindoline Derivative from Psychotria pilifera

Psychotripine, a trimeric pyrroloindoline derivative with an unprecedented hendecacyclic system bearing a hexahydro-1,3,5-triazine unit, was isolated from the leaves of Psychotria pilifera. The structure was elucidated on the basis of spectroscopic and quantum theory. A possible biogenesis was also...

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Veröffentlicht in:Organic letters 2011-11, Vol.13 (21), p.5896-5899
Hauptverfasser: Li, Xiao-Ning, Zhang, Yu, Cai, Xiang-Hai, Feng, Tao, Liu, Ya-Ping, Li, Yan, Ren, Jie, Zhu, Hua-Jie, Luo, Xiao-Dong
Format: Artikel
Sprache:eng
Schlagworte:
Cell Line, Tumor
Cell Survival - drug effects
Humans
Indoles - chemistry
Indoles - pharmacology
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Leaves - chemistry
Psychotria - chemistry
Pyrroles - chemistry
Pyrroles - pharmacology
Quantum Theory
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Zusammenfassung:Psychotripine, a trimeric pyrroloindoline derivative with an unprecedented hendecacyclic system bearing a hexahydro-1,3,5-triazine unit, was isolated from the leaves of Psychotria pilifera. The structure was elucidated on the basis of spectroscopic and quantum theory. A possible biogenesis was also postulated.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol202536b