Scalarane Sesterterpenes from the Sponge Smenospongia sp

Ten new sesterterpene compounds (4−13) and seven known metabolites (1−3, 14−17) were isolated from the sponge Smenospongia sp. collected from Korean coastal waters. On the basis of combined spectroscopic analyses, the new compounds exhibited diverse functionalities on a common scalarane sesterterpen...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2008-11, Vol.71 (11), p.1866-1871
Hauptverfasser:	Song, Jueun, Jeong, Wooyeol, Wang, Nan, Lee, Hyi-Seung, Sim, Chung J, Oh, Ki-Bong, Shin, Jongheon
Format:	Artikel
Sprache:	eng
Schlagworte:	acetoxyscalarin acetylscalarin Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology anticarcinogenic activity Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Biological and medical sciences chemical structure cultured cells cytotoxicity Drug Screening Assays, Antitumor enzyme inhibition furanosesterterpenes General pharmacology Humans hydroxyheteronemin isocitrate lyase Isocitrate Lyase - antagonists & inhibitors K562 Cells Medical sciences medicinal properties Microbial Sensitivity Tests Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Porifera Porifera - chemistry scalarane sesquiterpenes sesquiterpenoids Sesterterpenes - chemistry Sesterterpenes - isolation & purification Sesterterpenes - pharmacology smenospongia spectral analysis
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