Neonatal intensive care unit stress is associated with brain development in preterm infants

Objective: Although many perinatal factors have been linked to adverse neurodevelopmental outcomes in very premature infants, much of the variation in outcome remains unexplained. The impact on brain development of 1 potential factor, exposure to stressors in the neonatal intensive care unit, has no...

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Veröffentlicht in:	Annals of neurology 2011-10, Vol.70 (4), p.541-549
Hauptverfasser:	Smith, Gillian C., Gutovich, Jordan, Smyser, Christopher, Pineda, Roberta, Newnham, Carol, Tjoeng, Tiong H., Vavasseur, Claudine, Wallendorf, Michael, Neil, Jeffrey, Inder, Terrie
Format:	Artikel
Sprache:	eng
Schlagworte:	Babies Biological and medical sciences Brain - pathology Developmental Disabilities - pathology Developmental Disabilities - psychology Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Humans Infant Behavior - psychology Infant, Newborn Infant, Premature - growth & development Infant, Premature - psychology Intensive care Intensive Care Units, Neonatal Magnetic Resonance Imaging Male Medical research Medical sciences Neurology NMR Nuclear magnetic resonance Pregnancy Pregnancy. Fetus. Placenta Prospective Studies Risk Factors
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Zusammenfassung:	Objective: Although many perinatal factors have been linked to adverse neurodevelopmental outcomes in very premature infants, much of the variation in outcome remains unexplained. The impact on brain development of 1 potential factor, exposure to stressors in the neonatal intensive care unit, has not yet been studied in a systematic, prospective manner. Methods: In this prospective cohort study of infants born at
ISSN:	0364-5134 1531-8249
DOI:	10.1002/ana.22545