Immunological failure despite virological suppression in HIV seropositive individuals on antiretroviral therapy

Some individuals experience a discordant response during antiretroviral therapy (ART), with a blunted CD4+ cell count response despite low HIV-1 RNA plasma levels. CD4 counts and viral load of 251 individuals on ART referred to the center were analysed for immunological failure. The viral load tests...

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Veröffentlicht in:	Indian Journal of Sexually Transmitted Diseases and AIDS 2011-07, Vol.32 (2), p.94-98
Hauptverfasser:	Prabhakar, B, Banu, Asima, Pavithra, H B, Chandrashekhara, P, Sasthri, Suresh
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Analysis Antiretroviral drugs Antiviral agents Drug therapy Health aspects Highly active antiretroviral therapy HIV HIV (Viruses) Human immunodeficiency virus Immunology Patient outcomes Pediatrics Physiological aspects Regression analysis T cells
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Zusammenfassung:	Some individuals experience a discordant response during antiretroviral therapy (ART), with a blunted CD4+ cell count response despite low HIV-1 RNA plasma levels. CD4 counts and viral load of 251 individuals on ART referred to the center were analysed for immunological failure. The viral load tests of 28 patients revealed a discordant response, characterized by low CD4 counts despite viral suppression (
ISSN:	2589-0557 1998-3816 2589-0565
DOI:	10.4103/0253-7184.85412