Ultrastructural analysis, zinc transporters, glucose transporters and hormones expression in new world primate ( Callithrix jacchus ) and human pancreatic islets

Highlights ► New world primate islets have not yet been studied in comparison to human islets. ► New world primate islets are smaller than human islets but have similar cell content. ► New world primate islets express comparable zinc transporters to human islets. ► Zinc transporter ZIP14 was found f...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	General and comparative endocrinology 2011-11, Vol.174 (2), p.71-79
Hauptverfasser:	Mohanasundaram, Daisy, Drogemuller, Chris, Brealey, John, Jessup, Claire F, Milner, Clyde, Murgia, Chiara, Lang, Carol J, Milton, Austin, Zalewski, Peter D, Russ, Graeme R, Coates, Patrick T
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals Callithrix - metabolism Callithrix jacchus Carrier Proteins - genetics Carrier Proteins - metabolism diabetes Endocrinology & Metabolism Fluorescent Antibody Technique gene expression glucagon glucagon-like peptide 1 glucokinase Glucose Transport Proteins, Facilitative - genetics Glucose Transport Proteins, Facilitative - metabolism Glucose Transporter Type 2 - genetics Glucose Transporter Type 2 - metabolism glucose transporters Humans insulin islets of Langerhans Islets of Langerhans - metabolism Islets of Langerhans - ultrastructure Marmoset ( Callithrix jacchus) messenger RNA Microscopy, Electron Pancreatic islets protein synthesis Real-Time Polymerase Chain Reaction somatostatin swine Transporters Ultrastructure Zinc
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights ► New world primate islets have not yet been studied in comparison to human islets. ► New world primate islets are smaller than human islets but have similar cell content. ► New world primate islets express comparable zinc transporters to human islets. ► Zinc transporter ZIP14 was found for the first time in human and primate islets. ► New world primate islets are comparable to humans and a novel model for diabetes.
ISSN:	0016-6480 1095-6840
DOI:	10.1016/j.ygcen.2011.07.004