Recurrent autoimmune hemolytic anemia induced by XELOX chemotherapy for colon cancer
We describe a 54-year old woman with oxaliplatin-induced autoimmune hemolytic anemia and review the clinical features of similar published cases. The present patient had metastatic colon cancer and was admitted to our hospital with a floating sensation and general malaise on day 4 after undergoing t...
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Veröffentlicht in: | Nippon Shokakibyo Gakkai Zasshi 2011, Vol.108(10), pp.1712-1719 |
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Hauptverfasser: | , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | jpn |
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Zusammenfassung: | We describe a 54-year old woman with oxaliplatin-induced autoimmune hemolytic anemia and review the clinical features of similar published cases. The present patient had metastatic colon cancer and was admitted to our hospital with a floating sensation and general malaise on day 4 after undergoing the last of 4 cycles of a 7th round of chemotherapy with XELOX. Laboratory data revealed 4.6g/dl hemoglobin and 8.77mg/dl creatinine. Direct and indirect Coombs tests of a blood sample for blood transfusion were both positive. We diagnosed immune hemolysis with acute renal failure based on the clinical course and blood samples showing haptoglobin |
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ISSN: | 0446-6586 1349-7693 |
DOI: | 10.11405/nisshoshi.108.1712 |