Cell communication networks in cancer invasion

Cell communication networks in cancer invasion

Highlights ► A complex network of inter-cellular communication enables cancer cell invasion. ► Growth factors, proteases, matrix physics and metabolite levels enable communication. ► The network is plastic and changes during metastasis and in response to therapy.

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Bibliographische Detailangaben
Veröffentlicht in:Current opinion in cell biology 2011-10, Vol.23 (5), p.621-629
Hauptverfasser: Calvo, Fernando, Sahai, Erik
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Communication
Extracellular Matrix - metabolism
Humans
Internal Medicine
Neoplasm Metastasis
Neoplasms - metabolism
Neoplasms - pathology
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Beschreibung
Zusammenfassung:Highlights ► A complex network of inter-cellular communication enables cancer cell invasion. ► Growth factors, proteases, matrix physics and metabolite levels enable communication. ► The network is plastic and changes during metastasis and in response to therapy.
ISSN:0955-0674
1879-0410
DOI:10.1016/j.ceb.2011.04.010