The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics

ObjectiveThe European Registry on Cushing's syndrome (ERCUSYN) is designed to collect prospective and follow-up data at EU level on Cushing's syndrome (CS).Design and methodsBaseline data on 481 CS patients (390 females, 91 males; mean age (±s.d.): 44±14 years) collected from 36 centres in...

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Veröffentlicht in:	European journal of endocrinology 2011-09, Vol.165 (3), p.383-392
Hauptverfasser:	Valassi, Elena, Santos, Alicia, Yaneva, Maria, Tóth, Miklós, Strasburger, Christian J, Chanson, Philippe, Wass, John A H, Chabre, Olivier, Pfeifer, Marija, Feelders, Richard A, Tsagarakis, Stylianos, Trainer, Peter J, Franz, Holger, Zopf, Kathrin, Zacharieva, Sabina, Lamberts, Steven W J, Tabarin, Antoine, Webb, Susan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenal Gland Neoplasms - complications Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adult Aged Aged, 80 and over Biological and medical sciences Bone Diseases, Metabolic - etiology Clinical Study Cohort Studies Cushing Syndrome - complications Cushing Syndrome - epidemiology Cushing Syndrome - etiology Endocrinopathies Europe - epidemiology Female Fractures, Bone - etiology Fundamental and applied biological sciences. Psychology Humans Male Medical sciences Middle Aged Miscellaneous Non tumoral diseases. Target tissue resistance. Benign neoplasms Pituitary Neoplasms - complications Prevalence Prospective Studies Public health. Hygiene Public health. Hygiene-occupational medicine Quality of Life Registries Retrospective Studies Vertebrates: endocrinology
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Zusammenfassung:	ObjectiveThe European Registry on Cushing's syndrome (ERCUSYN) is designed to collect prospective and follow-up data at EU level on Cushing's syndrome (CS).Design and methodsBaseline data on 481 CS patients (390 females, 91 males; mean age (±s.d.): 44±14 years) collected from 36 centres in 23 countries, including new patients from 2008 and retrospective cases since 2000. Patients were divided into four major aetiologic groups: pituitary-dependent CS (PIT-CS) (66%), adrenal-dependent CS (ADR-CS) (27%), CS from an ectopic source (ECT-CS) (5%) and CS from other aetiologies (2%).ResultsProportion of men in the ECT-CS group was higher than in the other groups (P
ISSN:	0804-4643 1479-683X
DOI:	10.1530/EJE-11-0272