A Prospective, Randomized Controlled Study Comparing Lidocaine and Tramadol in Periprostatic Nerve Blockage for Transrectal Ultrasound-guided Prostate Biopsy
Objectives To assess the efficacy of tramadol and lidocaine in reducing pain using the periprostatic nerve block technique with a spinal needle, guided by transrectal ultrasound (TRUS) before the biopsy application. Methods Of the 112 eligible candidates who were asked to participate in the study, 9...
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| Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 2011-08, Vol.78 (2), p.257-260 |
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| creator | Seçkiner, Ilker Sen, Haluk Erturhan, Sakıp Yağcı, Faruk |
| description | Objectives To assess the efficacy of tramadol and lidocaine in reducing pain using the periprostatic nerve block technique with a spinal needle, guided by transrectal ultrasound (TRUS) before the biopsy application. Methods Of the 112 eligible candidates who were asked to participate in the study, 90 agreed and provided informed consent. These 90 men were randomized into 3 groups. Group 1 (n = 30) received lidocaine, group 2 (n = 29) received tramadol, and group 3 (n = 31) received saline solution. Within 10 minutes of biopsy procedure completion, the patients were presented with visual pain scales and asked to rate the pain. The patients also asked whether they would be to return for this procedure if it became medically necessary. Results The postprocedural mean pain scores of lidocaine, tramadol, and placebo groups were found to be 1.73, 2.89, and 4.32, respectively. The mean pain scores were significantly lower in both the lidocaine and the tramadol groups compared with the placebo group ( P |
| doi_str_mv | 10.1016/j.urology.2011.03.010 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_893341112</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S009042951100272X</els_id><sourcerecordid>893341112</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-4721749412a8026cb0ee3ef4b1325dc7e37a9baf303ea676f7c607cc93d200293</originalsourceid><addsrcrecordid>eNqFks-O0zAQxiMEYsvCI4B8QVxIGdtJvL6Almr5I1VQsbsSN8u1J5W7TlzspFL3XXhXHLWAxIWTLes3842_b4riOYU5Bdq82c7HGHzYHOYMKJ0DnwOFB8WM1kyUUsr6YTEDkFBWTNZnxZOUtgDQNI14XJwx2gBlNcyKn5dkFUPaoRncHl-Tb7q3oXP3aMki9EOW8Pl6PYz2kB-6nY6u35Cls8Fo1yPJOLmJutM2eOJ6ssLodrnhoAdnyBeMeyTvfTB3eoOkDXGC-xSznPbk1g9RpzD2ttyMzmah1bE017iwS4enxaNW-4TPTud5cfvh6mbxqVx-_fh5cbksTSWqoawEo6KSFWX6Alhj1oDIsa3WlLPaGoFcaLnWLQeOuhFNK0wDwhjJLQNgkp8Xr4598-g_RkyD6lwy6L3uMYxJXUjOK0opy2R9JE2eNP-jVbvoOh0PioKaglFbdQpGTcEo4CoHk-tenBTGdYf2T9XvJDLw8gToZLRvs03Gpb9cVQGXvMncuyOH2Y-9w6iScdgbtG5yVdng_jvK2386GO96l0Xv8IBpG8bYZ7MVVYkpUNfTFk1LRGn2SrDv_BdsAMaI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>893341112</pqid></control><display><type>article</type><title>A Prospective, Randomized Controlled Study Comparing Lidocaine and Tramadol in Periprostatic Nerve Blockage for Transrectal Ultrasound-guided Prostate Biopsy</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Seçkiner, Ilker ; Sen, Haluk ; Erturhan, Sakıp ; Yağcı, Faruk</creator><creatorcontrib>Seçkiner, Ilker ; Sen, Haluk ; Erturhan, Sakıp ; Yağcı, Faruk</creatorcontrib><description>Objectives To assess the efficacy of tramadol and lidocaine in reducing pain using the periprostatic nerve block technique with a spinal needle, guided by transrectal ultrasound (TRUS) before the biopsy application. Methods Of the 112 eligible candidates who were asked to participate in the study, 90 agreed and provided informed consent. These 90 men were randomized into 3 groups. Group 1 (n = 30) received lidocaine, group 2 (n = 29) received tramadol, and group 3 (n = 31) received saline solution. Within 10 minutes of biopsy procedure completion, the patients were presented with visual pain scales and asked to rate the pain. The patients also asked whether they would be to return for this procedure if it became medically necessary. Results The postprocedural mean pain scores of lidocaine, tramadol, and placebo groups were found to be 1.73, 2.89, and 4.32, respectively. The mean pain scores were significantly lower in both the lidocaine and the tramadol groups compared with the placebo group ( P <.001). In addition, statistically significant differences were found among the 3 groups regarding how willing they would be to return for the procedure if necessary. Conclusions In this study, we showed that the local anesthetic effect of tramadol in decreasing pain in periprostatic nerve block during TRUS-guided biopsy. The use of tramadol for pain relief in transrectal ultrasound-guided prostate biopsy is a practical, effective, and comfortable method compared with the results of the control group.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2011.03.010</identifier><identifier>PMID: 21601250</identifier><identifier>CODEN: URGYAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Analgesics, Opioid - therapeutic use ; Anesthetics, Local - therapeutic use ; Biological and medical sciences ; Biopsy, Needle - methods ; Double-Blind Method ; Humans ; Lidocaine - therapeutic use ; Male ; Medical sciences ; Middle Aged ; Nephrology. Urinary tract diseases ; Nerve Block ; Prospective Studies ; Prostate - innervation ; Prostatic Neoplasms - diagnostic imaging ; Prostatic Neoplasms - pathology ; Tramadol - therapeutic use ; Ultrasonography, Interventional ; Urology</subject><ispartof>Urology (Ridgewood, N.J.), 2011-08, Vol.78 (2), p.257-260</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-4721749412a8026cb0ee3ef4b1325dc7e37a9baf303ea676f7c607cc93d200293</citedby><cites>FETCH-LOGICAL-c474t-4721749412a8026cb0ee3ef4b1325dc7e37a9baf303ea676f7c607cc93d200293</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S009042951100272X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24403936$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21601250$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Seçkiner, Ilker</creatorcontrib><creatorcontrib>Sen, Haluk</creatorcontrib><creatorcontrib>Erturhan, Sakıp</creatorcontrib><creatorcontrib>Yağcı, Faruk</creatorcontrib><title>A Prospective, Randomized Controlled Study Comparing Lidocaine and Tramadol in Periprostatic Nerve Blockage for Transrectal Ultrasound-guided Prostate Biopsy</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>Objectives To assess the efficacy of tramadol and lidocaine in reducing pain using the periprostatic nerve block technique with a spinal needle, guided by transrectal ultrasound (TRUS) before the biopsy application. Methods Of the 112 eligible candidates who were asked to participate in the study, 90 agreed and provided informed consent. These 90 men were randomized into 3 groups. Group 1 (n = 30) received lidocaine, group 2 (n = 29) received tramadol, and group 3 (n = 31) received saline solution. Within 10 minutes of biopsy procedure completion, the patients were presented with visual pain scales and asked to rate the pain. The patients also asked whether they would be to return for this procedure if it became medically necessary. Results The postprocedural mean pain scores of lidocaine, tramadol, and placebo groups were found to be 1.73, 2.89, and 4.32, respectively. The mean pain scores were significantly lower in both the lidocaine and the tramadol groups compared with the placebo group ( P <.001). In addition, statistically significant differences were found among the 3 groups regarding how willing they would be to return for the procedure if necessary. Conclusions In this study, we showed that the local anesthetic effect of tramadol in decreasing pain in periprostatic nerve block during TRUS-guided biopsy. The use of tramadol for pain relief in transrectal ultrasound-guided prostate biopsy is a practical, effective, and comfortable method compared with the results of the control group.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Anesthetics, Local - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle - methods</subject><subject>Double-Blind Method</subject><subject>Humans</subject><subject>Lidocaine - therapeutic use</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Nerve Block</subject><subject>Prospective Studies</subject><subject>Prostate - innervation</subject><subject>Prostatic Neoplasms - diagnostic imaging</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Tramadol - therapeutic use</subject><subject>Ultrasonography, Interventional</subject><subject>Urology</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFks-O0zAQxiMEYsvCI4B8QVxIGdtJvL6Almr5I1VQsbsSN8u1J5W7TlzspFL3XXhXHLWAxIWTLes3842_b4riOYU5Bdq82c7HGHzYHOYMKJ0DnwOFB8WM1kyUUsr6YTEDkFBWTNZnxZOUtgDQNI14XJwx2gBlNcyKn5dkFUPaoRncHl-Tb7q3oXP3aMki9EOW8Pl6PYz2kB-6nY6u35Cls8Fo1yPJOLmJutM2eOJ6ssLodrnhoAdnyBeMeyTvfTB3eoOkDXGC-xSznPbk1g9RpzD2ttyMzmah1bE017iwS4enxaNW-4TPTud5cfvh6mbxqVx-_fh5cbksTSWqoawEo6KSFWX6Alhj1oDIsa3WlLPaGoFcaLnWLQeOuhFNK0wDwhjJLQNgkp8Xr4598-g_RkyD6lwy6L3uMYxJXUjOK0opy2R9JE2eNP-jVbvoOh0PioKaglFbdQpGTcEo4CoHk-tenBTGdYf2T9XvJDLw8gToZLRvs03Gpb9cVQGXvMncuyOH2Y-9w6iScdgbtG5yVdng_jvK2386GO96l0Xv8IBpG8bYZ7MVVYkpUNfTFk1LRGn2SrDv_BdsAMaI</recordid><startdate>20110801</startdate><enddate>20110801</enddate><creator>Seçkiner, Ilker</creator><creator>Sen, Haluk</creator><creator>Erturhan, Sakıp</creator><creator>Yağcı, Faruk</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110801</creationdate><title>A Prospective, Randomized Controlled Study Comparing Lidocaine and Tramadol in Periprostatic Nerve Blockage for Transrectal Ultrasound-guided Prostate Biopsy</title><author>Seçkiner, Ilker ; Sen, Haluk ; Erturhan, Sakıp ; Yağcı, Faruk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-4721749412a8026cb0ee3ef4b1325dc7e37a9baf303ea676f7c607cc93d200293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Anesthetics, Local - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle - methods</topic><topic>Double-Blind Method</topic><topic>Humans</topic><topic>Lidocaine - therapeutic use</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Nerve Block</topic><topic>Prospective Studies</topic><topic>Prostate - innervation</topic><topic>Prostatic Neoplasms - diagnostic imaging</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Tramadol - therapeutic use</topic><topic>Ultrasonography, Interventional</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Seçkiner, Ilker</creatorcontrib><creatorcontrib>Sen, Haluk</creatorcontrib><creatorcontrib>Erturhan, Sakıp</creatorcontrib><creatorcontrib>Yağcı, Faruk</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Seçkiner, Ilker</au><au>Sen, Haluk</au><au>Erturhan, Sakıp</au><au>Yağcı, Faruk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Prospective, Randomized Controlled Study Comparing Lidocaine and Tramadol in Periprostatic Nerve Blockage for Transrectal Ultrasound-guided Prostate Biopsy</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>2011-08-01</date><risdate>2011</risdate><volume>78</volume><issue>2</issue><spage>257</spage><epage>260</epage><pages>257-260</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><coden>URGYAZ</coden><abstract>Objectives To assess the efficacy of tramadol and lidocaine in reducing pain using the periprostatic nerve block technique with a spinal needle, guided by transrectal ultrasound (TRUS) before the biopsy application. Methods Of the 112 eligible candidates who were asked to participate in the study, 90 agreed and provided informed consent. These 90 men were randomized into 3 groups. Group 1 (n = 30) received lidocaine, group 2 (n = 29) received tramadol, and group 3 (n = 31) received saline solution. Within 10 minutes of biopsy procedure completion, the patients were presented with visual pain scales and asked to rate the pain. The patients also asked whether they would be to return for this procedure if it became medically necessary. Results The postprocedural mean pain scores of lidocaine, tramadol, and placebo groups were found to be 1.73, 2.89, and 4.32, respectively. The mean pain scores were significantly lower in both the lidocaine and the tramadol groups compared with the placebo group ( P <.001). In addition, statistically significant differences were found among the 3 groups regarding how willing they would be to return for the procedure if necessary. Conclusions In this study, we showed that the local anesthetic effect of tramadol in decreasing pain in periprostatic nerve block during TRUS-guided biopsy. The use of tramadol for pain relief in transrectal ultrasound-guided prostate biopsy is a practical, effective, and comfortable method compared with the results of the control group.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>21601250</pmid><doi>10.1016/j.urology.2011.03.010</doi><tpages>4</tpages></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Analgesics, Opioid - therapeutic use Anesthetics, Local - therapeutic use Biological and medical sciences Biopsy, Needle - methods Double-Blind Method Humans Lidocaine - therapeutic use Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nerve Block Prospective Studies Prostate - innervation Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - pathology Tramadol - therapeutic use Ultrasonography, Interventional Urology |
| title | A Prospective, Randomized Controlled Study Comparing Lidocaine and Tramadol in Periprostatic Nerve Blockage for Transrectal Ultrasound-guided Prostate Biopsy |
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