Effect of short term exposure of fenvalerate on biochemical and haematological responses in Labeo rohita (Hamilton) fingerlings

[Display omitted] ► We study the effects of short term exposure to fenvalerate in carp, Labeo rohita. ► Fenvalerate cause inhibition of antioxidant enzymes in liver and gill tissues. ► High transaminase activities resulted due to increased oxidative stress. ► Haematological alterations further corroborated the toxic effect of fenvalerate. Experiment was carried out to determine the median lethal concentration (LC 50) of fenvalerate to Labeo rohita fingerlings. After determining the LC 50 value of fenvalerate, a sub-lethal concentration (1/3rd of LC 50) of fenvalerate was exposed for 15 days. Significant alterations in SOD ( P < 0.05) activity of liver and gill was observed due to fenvalerate. Catalase activity in gills of fishes was also affected significantly ( P < 0.05). WBC, NBT and Hct values were reduced significantly in fenvalerate exposed fishes as compared to control group, whereas blood glucose level showed higher values in fenvalerate exposed group. Serum total protein and albumin were also reduced significantly as a result of fenvalerate exposure. Significant increase in the serum GOT, serum GPT, creatinine, triglyceride and serum ACP was noticed after 15 days of fenvalerate exposure. Results indicated that short term exposure of fenvalerate can induce biochemical and haematological alterations causing stress to L. rohita fingerlings.