Lack of association of the RTN4R genetic variations with risk of schizophrenia and SPEM abnormality in a Korean population

Abstract This study examined the association of the reticulon 4 receptor ( RTN4R ) gene with schizophrenia and smooth pursuit eye movement (SPEM) abnormality in a Korean population. Although we failed to provide convincing evidence that RTN4R is associated with schizophrenia development and SPEM imp...

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Veröffentlicht in:	Psychiatry research 2011-09, Vol.189 (2), p.312-314
Hauptverfasser:	Pasaje, Charisse Flerida A, Bae, Joon Seol, Park, Byung-Lae, Park, Chul Soo, Kim, Bong-Jo, Lee, Cheol-Soon, Kim, Jae Won, Choi, Woo Hyuk, Shin, Tae-Min, Koh, In Song, Choi, Ihn-Geun, Woo, Sung-ll, Shin, Hyoung Doo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Biological and medical sciences Electrooculography - methods Female Genetic Predisposition to Disease - genetics Genome-Wide Association Study GPI-Linked Proteins - genetics Humans Male Medical sciences Myelin Proteins - genetics Nogo Receptor 1 Ocular Motility Disorders - genetics Polymorphism, Single Nucleotide - genetics Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Pursuit, Smooth - genetics Receptors, Cell Surface - genetics Regression Analysis Republic of Korea Risk Factors RTN4R Schizophrenia Schizophrenia - genetics Single nucleotide polymorphism
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Zusammenfassung:	Abstract This study examined the association of the reticulon 4 receptor ( RTN4R ) gene with schizophrenia and smooth pursuit eye movement (SPEM) abnormality in a Korean population. Although we failed to provide convincing evidence that RTN4R is associated with schizophrenia development and SPEM impairment, our findings may be useful for further genetic studies.
ISSN:	0165-1781 1872-7123
DOI:	10.1016/j.psychres.2011.02.006