The Association of Blood Component Use Ratios With the Survival of Massively Transfused Trauma Patients With and Without Severe Brain Injury

The Association of Blood Component Use Ratios With the Survival of Massively Transfused Trauma Patients With and Without Severe Brain Injury

BACKGROUND:The effect of blood component ratios on the survival of patients with traumatic brain injury (TBI) has not been studied. METHODS:A database of patients transfused in the first 24 hours after admission for injury from 22 Level I trauma centers over an 18-month period was queried to find pa...

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Veröffentlicht in:The journal of trauma 2011-08, Vol.71 (2 Suppl 3, Topics in the Management of Substantial Hemorrhage), p.S343-S352
Hauptverfasser: Spinella, Philip C., Wade, Charles E., Blackbourne, Lorne H., Borgman, Matthew A., Zarzabal, Lee A., Du, Fei, Perkins, Jeremy G., Maegele, Marc, Schreiber, Martin, Hess, John R., Jastrow, Kenneth M., Gonzalez, Ernest A., Holcomb, John B., Kozar, Rosemary
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Blood Component Transfusion
Brain Injuries - blood
Brain Injuries - mortality
Brain Injuries - therapy
Erythrocyte Count
Female
Humans
Male
Middle Aged
Platelet Count
Retrospective Studies
Survival Rate
Trauma Centers
Treatment Outcome
Young Adult
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Zusammenfassung:BACKGROUND:The effect of blood component ratios on the survival of patients with traumatic brain injury (TBI) has not been studied. METHODS:A database of patients transfused in the first 24 hours after admission for injury from 22 Level I trauma centers over an 18-month period was queried to find patients who (1) met different definitions of massive transfusion (5 units red blood cell [RBC] in 6 hours vs. 10 units RBC in 24 hours), (2) received high or low ratios of platelets or plasma to RBC units (
ISSN:0022-5282
1529-8809
DOI:10.1097/TA.0b013e318227ef2d