Amniotic membrane and amniotic cells: Potential therapeutic tools to combat tissue inflammation and fibrosis?

Abstract In addition to the placenta, umbilical cord and amniotic fluid, the amniotic membrane is emerging as an immensely valuable and easily accessible source of stem and progenitor cells. This concise review will focus on the stem/progenitor cell properties of human amniotic epithelial and mesenc...

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Veröffentlicht in:	Placenta (Eastbourne) 2011-10, Vol.32, p.S320-S325
Hauptverfasser:	Manuelpillai, U, Moodley, Y, Borlongan, C.V, Parolini, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Amnion - cytology Amniotic epithelial cells Amniotic membrane Amniotic mesenchymal stromal cells Animals Cell Differentiation - physiology Female Fibrosis - surgery Humans Internal Medicine Mesenchymal Stromal Cells - cytology Obstetrics and Gynecology Placental stem cells Pregnancy Stem Cell Transplantation - methods Stem Cells - cytology Tissue inflammation
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Beschreibung
Zusammenfassung:	Abstract In addition to the placenta, umbilical cord and amniotic fluid, the amniotic membrane is emerging as an immensely valuable and easily accessible source of stem and progenitor cells. This concise review will focus on the stem/progenitor cell properties of human amniotic epithelial and mesenchymal stromal cells and evaluate the effects exerted by these cells and the amniotic membrane on tissue inflammation and fibrosis.
ISSN:	0143-4004 1532-3102
DOI:	10.1016/j.placenta.2011.04.010