Clinical utility of dual-energy CT for evaluation of tophaceous gout
Although diagnosing gout generally is straightforward, atypical disease may present a challenge if it is associated with unusual symptoms or sites, discordant serum urate level, or mimics of gout. Dual-energy computed tomography (CT) may be used to differentiate urate crystals from calcium by using...
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Veröffentlicht in: | Radiographics 2011-09, Vol.31 (5), p.1365-1375 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Although diagnosing gout generally is straightforward, atypical disease may present a challenge if it is associated with unusual symptoms or sites, discordant serum urate level, or mimics of gout. Dual-energy computed tomography (CT) may be used to differentiate urate crystals from calcium by using specific attenuation characteristics, which may help diagnose gout. In patients with known tophaceous gout, dual-energy CT may be used for serial volumetric quantification of subclinical tophi to evaluate response to treatment. Given the utility of dual-energy CT in challenging cases and its ability to provide an objective outcomes measure in patients with tophaceous gout, dual-energy CT promises to be a unique and clinically relevant modality in the diagnosis and management of gout. |
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ISSN: | 0271-5333 1527-1323 |
DOI: | 10.1148/rg.315115510 |