Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm

Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm

We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media deriv...

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Veröffentlicht in:Journal of Biomedical Optics 2010-05, Vol.15 (3), p.037015-037015
Hauptverfasser: Nachabe, Rami, Hendriks, Benno H. W, Desjardins, Adrien E, van der Voort, Marjolein, van der Mark, Martin B, Sterenborg, Henricus J. C. M
Format: Artikel
Sprache:eng
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Diffusion
Diffusion theory
Emulsions
Lipids
Mathematical models
Media
Scattering
Spectra
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container_issue 3
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container_title Journal of Biomedical Optics
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creator Nachabe, Rami
Hendriks, Benno H. W
Desjardins, Adrien E
van der Voort, Marjolein
van der Mark, Martin B
Sterenborg, Henricus J. C. M
description We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe.
doi_str_mv 10.1117/1.3454392
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Diffusion
Diffusion theory
Emulsions
Lipids
Mathematical models
Media
Scattering
Spectra
title Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm
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