One-Step Preparation of Functionalized (E)-Vinylsilanes from Aldehydes

One-Step Preparation of Functionalized (E)-Vinylsilanes from Aldehydes

Functionalized (E)-vinylsilanes have been prepared in one step from a wide range of aldehydes, via a chromium(II)-mediated olefination with novel dihalomethylsilane reagents, in moderate to excellent yields and with excellent stereoselectivity.

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Veröffentlicht in:Organic letters 2011-09, Vol.13 (18), p.4806-4809
Hauptverfasser: Lim, Diane S. W, Anderson, Edward A
Format: Artikel
Sprache:eng
Schlagworte:
Aldehydes - chemistry
Chromium - chemistry
Molecular Structure
Silanes - chemical synthesis
Silanes - chemistry
Stereoisomerism
Vinyl Compounds - chemical synthesis
Vinyl Compounds - chemistry
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Zusammenfassung:Functionalized (E)-vinylsilanes have been prepared in one step from a wide range of aldehydes, via a chromium(II)-mediated olefination with novel dihalomethylsilane reagents, in moderate to excellent yields and with excellent stereoselectivity.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol201833u