Intraarterially delivered human umbilical cord blood-derived mesenchymal stem cells in canine cerebral ischemia

The present study examined the effects of human umbilical cord blood‐derived mesenchymal stem cells (HUCB‐derived MSCs) delivered through the basilar artery in a canine thromboembolic brain ischemia model. Cerebral ischemia was induced through occlusion of the middle cerebral artery by injecting thr...

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Veröffentlicht in:	Journal of neuroscience research 2009-12, Vol.87 (16), p.3554-3567
Hauptverfasser:	Chung, Dai-Jung, Choi, Chi-Bong, Lee, Sung-Ho, Kang, Eun-Hee, Lee, Jae-Hoon, Hwang, Soo-Han, Han, Hoon, Lee, Jong-Hwan, Choe, Bo-Young, Lee, Soo-Yeol, Kim, Hwi-Yool
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes Astrocytes - metabolism Astrocytes - pathology Blood Brain - metabolism Brain - pathology Brain Ischemia - metabolism Brain Ischemia - pathology Brain Ischemia - therapy Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - metabolism canine Cardiovascular system Cell Differentiation - physiology Cerebral blood flow cerebral ischemia Cord Blood Stem Cell Transplantation Dogs Endothelial cells Fluorescent Antibody Technique HUBC-derived MSCs Humans Image processing Infarction, Middle Cerebral Artery - metabolism Infarction, Middle Cerebral Artery - pathology Infarction, Middle Cerebral Artery - therapy interventional endovascular approach intraarterial transplantation Ischemia Magnetic Resonance Imaging Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells Mesenchyme middle cerebral artery occlusion Nervous system Neurons Neurons - metabolism Neurons - pathology Neuroprotection Recovery of Function Statistics, Nonparametric Stem cells Thromboembolism Time Factors Transplantation Transplantation, Heterologous Umbilical cord Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism Von Willebrand factor von Willebrand Factor - metabolism
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