Infliximab-induced lupus erythematosus in a case of ulcerative colitis

Infliximab is widely used in the treatment of inflammatory bowel disease, but despite its good clinical efficacy and tolerance, drug-induced autoimmune disorders have been reported as adverse reactions and are a matter of concern. Here we report a patient with ulcerative colitis who developed drug-i...

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Veröffentlicht in:Nippon Shokakibyo Gakkai Zasshi 2011, Vol.108(9), pp.1535-1539
Hauptverfasser: NISHIKAWA, Jun, MIYAZAKI, Takako, SUZUKI, Nobuhiro, ITAYA, Yuko, YAMAWAKI, Hidemoto, MIHARA, Hiroshi, HASUMOTO, Yushi, FUJINAMI, Haruka, OGAWA, Kohei, HOSOKAWA, Ayumu, KUDO, Takahiko, SUGIYAMA, Toshiro
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container_end_page 1539
container_issue 9
container_start_page 1535
container_title Nippon Shokakibyo Gakkai Zasshi
container_volume 108
creator NISHIKAWA, Jun
MIYAZAKI, Takako
SUZUKI, Nobuhiro
ITAYA, Yuko
YAMAWAKI, Hidemoto
MIHARA, Hiroshi
HASUMOTO, Yushi
FUJINAMI, Haruka
OGAWA, Kohei
HOSOKAWA, Ayumu
KUDO, Takahiko
SUGIYAMA, Toshiro
description Infliximab is widely used in the treatment of inflammatory bowel disease, but despite its good clinical efficacy and tolerance, drug-induced autoimmune disorders have been reported as adverse reactions and are a matter of concern. Here we report a patient with ulcerative colitis who developed drug-induced lupus erythematosus after infliximab treatment. While this is a rare complication of infliximab, early diagnosis and successful management are essential.
doi_str_mv 10.11405/nisshoshi.108.1535
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source MEDLINE; EZB Electronic Journals Library
subjects Adult
Anti-Inflammatory Agents - adverse effects
Antibodies, Monoclonal - adverse effects
Colitis, Ulcerative - drug therapy
Female
Humans
Infliximab
Lupus Erythematosus, Systemic - chemically induced
title Infliximab-induced lupus erythematosus in a case of ulcerative colitis
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