Infliximab-induced lupus erythematosus in a case of ulcerative colitis

Infliximab is widely used in the treatment of inflammatory bowel disease, but despite its good clinical efficacy and tolerance, drug-induced autoimmune disorders have been reported as adverse reactions and are a matter of concern. Here we report a patient with ulcerative colitis who developed drug-i...

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Veröffentlicht in:Nippon Shokakibyo Gakkai Zasshi 2011, Vol.108(9), pp.1535-1539
Hauptverfasser: NISHIKAWA, Jun, MIYAZAKI, Takako, SUZUKI, Nobuhiro, ITAYA, Yuko, YAMAWAKI, Hidemoto, MIHARA, Hiroshi, HASUMOTO, Yushi, FUJINAMI, Haruka, OGAWA, Kohei, HOSOKAWA, Ayumu, KUDO, Takahiko, SUGIYAMA, Toshiro
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Sprache:jpn
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Zusammenfassung:Infliximab is widely used in the treatment of inflammatory bowel disease, but despite its good clinical efficacy and tolerance, drug-induced autoimmune disorders have been reported as adverse reactions and are a matter of concern. Here we report a patient with ulcerative colitis who developed drug-induced lupus erythematosus after infliximab treatment. While this is a rare complication of infliximab, early diagnosis and successful management are essential.
ISSN:0446-6586
1349-7693
DOI:10.11405/nisshoshi.108.1535