Diabetes in pregnancy may differentially affect neonatal outcomes for twins and singletons

Diabet. Med. 28, 1068–1073 (2011) Aim We tested the hypothesis that diabetes in pregnancy may differentially affect neonatal outcomes in twin vs. singleton pregnancies. Methods In a retrospective cohort analysis of twins (n = 422 068) and singletons (n = 14 298 367) born in the USA from 1998 to 20...

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Veröffentlicht in:	Diabetic medicine 2011-09, Vol.28 (9), p.1068-1073
Hauptverfasser:	Luo, Z. C., Simonet, F., Wei, S. Q., Xu, H., Rey, E., Fraser, W. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-min Apgar score Adult Apgar Score Biological and medical sciences congenital anomalies diabetes in pregnancy Endocrinopathies Feeding. Feeding behavior Female Fetal Growth Retardation - epidemiology Fundamental and applied biological sciences. Psychology Humans Infant, Newborn Maternal Age Medical sciences neonatal death Parity Pregnancy Pregnancy in Diabetics - epidemiology Pregnancy Outcome - epidemiology Pregnancy, Multiple Retrospective Studies Twins Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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Zusammenfassung:	Diabet. Med. 28, 1068–1073 (2011) Aim We tested the hypothesis that diabetes in pregnancy may differentially affect neonatal outcomes in twin vs. singleton pregnancies. Methods In a retrospective cohort analysis of twins (n = 422 068) and singletons (n = 14 298 367) born in the USA from 1998 to 2001, we evaluated the adjusted odds ratios of adverse neonatal outcomes comparing diabetic vs. non‐diabetic pregnancies, controlling for maternal characteristics. Primary outcomes include macrosomia (birthweight for gestational age > 90th percentile), congenital anomalies, low 5‐min Apgar score (
ISSN:	0742-3071 1464-5491
DOI:	10.1111/j.1464-5491.2011.03366.x