ATP13A2 variability in Taiwanese Parkinson's disease

Mutations in ATP13A2 have been reported to associate with Parkinson's disease (PD). This study investigates the contribution of genetic variants in ATP13A2 to Taiwanese PD. ATP13A2 cDNA fragments from 65 early onset PD (onset

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of medical genetics. Part B, Neuropsychiatric genetics Neuropsychiatric genetics, 2011-09, Vol.156B (6), p.720-729
Hauptverfasser:	Chen, Chiung-Mei, Lin, Chih-Hsin, Juan, Hsueh-Fen, Hu, Fen-Ju, Hsiao, Ya-Chin, Chang, Hsin-Yi, Chao, Chih-Ying, Chen, I-Cheng, Lee, Li-Ching, Wang, Tsu-Wei, Chen, Ya-Tang, Chen, Yi-Tsun, Lee-Chen, Guey-Jen, Wu, Yih-Ru
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Apoptosis ATP13A2 Base Sequence Biological and medical sciences Caspase 3 - biosynthesis Caspase 3 - metabolism Caspase-3 Cell Line, Tumor Cycloheximide Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases expression study Female Genetic Variation Humans Male Medical genetics Medical sciences Middle Aged Movement disorders Mutation mutation screening Neostriatum Nervous system (semeiology, syndromes) Nervous system as a whole Neurodegenerative diseases Neurology Oxidative Stress Parkinson Disease - genetics Parkinson Disease - metabolism Parkinson's disease protein structure modeling Protein Structure, Tertiary Proton-Translocating ATPases - chemistry Proton-Translocating ATPases - genetics RNA, Messenger - analysis RNA, Messenger - biosynthesis Sequence Analysis, DNA Single photon emission computed tomography Taiwan Transmembrane domains
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Mutations in ATP13A2 have been reported to associate with Parkinson's disease (PD). This study investigates the contribution of genetic variants in ATP13A2 to Taiwanese PD. ATP13A2 cDNA fragments from 65 early onset PD (onset
ISSN:	1552-4841 1552-485X 1552-485X
DOI:	10.1002/ajmg.b.31214