Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury

Highlights ► The manuscript explores the molecular pathways and subtypes of cells involved in the protective effect of palmitoylethanolamide in a model of spinal cord compression injury.

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Bibliographische Detailangaben
Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2011-08, Vol.25 (6), p.1099-1112
Hauptverfasser:	Esposito, Emanuela, Paterniti, Irene, Mazzon, Emanuela, Genovese, Tiziana, Di Paola, Rosanna, Galuppo, Maria, Cuzzocrea, Salvatore
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Astrocytes - chemistry Astrocytes - pathology CB2 Cell Degranulation - drug effects Chymases - secretion Disease Models, Animal Dopamine Plasma Membrane Transport Proteins - metabolism Drug Evaluation, Preclinical Endocannabinoids Ethanolamines GDNF Laminectomy Male Mast cells Mast Cells - drug effects Mast Cells - enzymology Mast Cells - secretion Mice Microglia - chemistry Microglia - pathology Myelitis - etiology Myelitis - pathology Myelitis - prevention & control Nerve Degeneration Nerve Growth Factors - secretion Neuroprotective Agents - administration & dosage Neuroprotective Agents - therapeutic use NGF NT-3 Palmitic Acids - administration & dosage Palmitic Acids - therapeutic use Psychiatry Random Allocation Receptor, Cannabinoid, CB2 - analysis Spinal Cord Compression - drug therapy Spinal Cord Compression - metabolism Spinal Cord Injuries - drug therapy Spinal Cord Injuries - metabolism Spinal cord injury Surgical Instruments Thoracic Vertebrae Tryptases - secretion
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Beschreibung
Zusammenfassung:	Highlights ► The manuscript explores the molecular pathways and subtypes of cells involved in the protective effect of palmitoylethanolamide in a model of spinal cord compression injury.
ISSN:	0889-1591 1090-2139
DOI:	10.1016/j.bbi.2011.02.006