Triphasic waves in a patient with tuberculous meningitis

Abstract We report on the case of a 32-year-old woman with tuberculous meningitis (TBM) with electroencephalogram (EEG) output displaying triphasic waves (TWs). The EEG on day 8 revealed generalized slowing, frontal bilateral TWs, a background of 2 Hz delta waves, and no epileptiform activity. The p...

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Veröffentlicht in:	Journal of the neurological sciences 2010-04, Vol.291 (1), p.114-117
Hauptverfasser:	Konno, Shingo, Sugimoto, Hideki, Nemoto, Hiroshi, Kitazono, Hisao, Murata, Mayumi, Toda, Takahiro, Nakazora, Hiroshi, Nomoto, Nobuatsu, Wakata, Nobuo, Kurihara, Teruyuki, Fujioka, Toshiki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alpha Rhythm Antitubercular Agents - therapeutic use Biological and medical sciences Brain - drug effects Brain - pathology Brain - physiopathology Diagnosis, Differential Electroencephalogram Electroencephalography Female Follow-Up Studies Humans Insulin-dependent diabetes mellitus Magnetic Resonance Imaging Medical sciences Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Time Factors Treatment Outcome Triphasic waves Tuberculosis, Meningeal - drug therapy Tuberculosis, Meningeal - pathology Tuberculosis, Meningeal - physiopathology Tuberculous meningitis
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Zusammenfassung:	Abstract We report on the case of a 32-year-old woman with tuberculous meningitis (TBM) with electroencephalogram (EEG) output displaying triphasic waves (TWs). The EEG on day 8 revealed generalized slowing, frontal bilateral TWs, a background of 2 Hz delta waves, and no epileptiform activity. The patient's condition improved slowly with antituberculosis chemotherapy treatment. A follow-up EEG on day 34 showed marked improvement, with no TWs, background activity improved to a 12 Hz symmetric alpha wave pattern, and no epileptiform activity, as before. To our knowledge, this is the first report of TWs observed in a TBM case.
ISSN:	0022-510X 1878-5883
DOI:	10.1016/j.jns.2009.12.027