Activation and Deactivation of a Chemical Transformation by an Electromagnetic Field: Evidence for Specific Microwave Effects in the Formation of Grignard Reagents
It's field density, not temperature! Modifying the electric field strength in a microwave experiment can completely change the outcome of a reaction. Whereas a low field strength in Grignard reagent formation from Mg metal and aryl halide leads to acceleration of the initiation step, using a hi...
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Veröffentlicht in: | Angewandte Chemie International Edition 2011-08, Vol.50 (33), p.7636-7640 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | It's field density, not temperature! Modifying the electric field strength in a microwave experiment can completely change the outcome of a reaction. Whereas a low field strength in Grignard reagent formation from Mg metal and aryl halide leads to acceleration of the initiation step, using a high field strength at the same temperature suppresses Mg insertion, favoring solvent decomposition and passivation of the Mg metal (see scheme). |
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ISSN: | 1433-7851 1521-3773 |
DOI: | 10.1002/anie.201100856 |