Use of 5-aminolevulinic acid for the confirmation of deep-seated brain tumors during stereotactic biopsy: Report of 2 cases

5-Aminolevulinic acid (ALA) has been successfully used to confirm the target tumor tissues obtained during stereotactic biopsy. The authors report their experience with 2 patients who underwent stereotactic biopsies of thalamic malignant lymphoma and pontine glioma utilizing 5-ALA. Intraoperatively,...

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Veröffentlicht in:	Journal of neurosurgery 2011-08, Vol.115 (2), p.278-280
Hauptverfasser:	MORIUCHI, Shusuke, YAMADA, Kimito, DEHARA, Makoto, TERAMOTO, Yoshifumi, SODA, Takao, IMAKITA, Masami, TANEDA, Mamoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aminolevulinic Acid Astrocytoma - diagnosis Astrocytoma - pathology Biological and medical sciences Biopsy - methods Brain Neoplasms - diagnosis Brain Neoplasms - pathology Child Female Humans Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - pathology Male Medical sciences Neurosurgery Pons - pathology Stereotaxic Techniques Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Thalamus - pathology
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Zusammenfassung:	5-Aminolevulinic acid (ALA) has been successfully used to confirm the target tumor tissues obtained during stereotactic biopsy. The authors report their experience with 2 patients who underwent stereotactic biopsies of thalamic malignant lymphoma and pontine glioma utilizing 5-ALA. Intraoperatively, the tumor specimens fluoresced, allowing for confirmation that the obtained target specimen contained tumor tissues. No serious side effects or complications occurred.
ISSN:	0022-3085 1933-0693
DOI:	10.3171/2011.4.JNS102137