Comparison of Prevalence, Clinical Course, and Pathological Findings of Left Ventricular Systolic Impairment Versus Normal Systolic Function in Patients With Hypertrophic Cardiomyopathy

Impaired left ventricular systolic function (ILVSF) in hypertrophic cardiomyopathy (HC) is a risk factor for sudden death and a determinant of high mortality. We determined its prevalence, clinical parameters, long-term outcome, and pathologic findings of explanted hearts. We retrospectively analyze...

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Veröffentlicht in:	The American journal of cardiology 2011-08, Vol.108 (4), p.548-555
Hauptverfasser:	Fernández, Adrián, MD, Vigliano, Carlos A., MD, Casabé, J. Horacio, MD, Diez, Mirta, MD, Favaloro, Liliana E., MD, Guevara, Eduardo, MD, Favaloro, Roberto R., MD, Laguens, Rubén P., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Cardiology Cardiology. Vascular system Cardiomyopathy, Hypertrophic - pathology Cardiomyopathy, Hypertrophic - physiopathology Cardiovascular Cardiovascular disease Female Heart Humans Male Medical sciences Middle Aged Myocarditis. Cardiomyopathies Pathology Prevalence Retrospective Studies Risk Factors Systole Veins & arteries Ventricular Dysfunction, Left - epidemiology Ventricular Dysfunction, Left - pathology Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:	Impaired left ventricular systolic function (ILVSF) in hypertrophic cardiomyopathy (HC) is a risk factor for sudden death and a determinant of high mortality. We determined its prevalence, clinical parameters, long-term outcome, and pathologic findings of explanted hearts. We retrospectively analyzed 382 patients with HC; ILVSF was characterized by LV ejection fraction
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2011.03.083