Differences in quantitative EEG between frontotemporal dementia and Alzheimer’s disease as revealed by LORETA

Research highlights ► A comparative study of frontotemporal dementia (FTD), Alzheimer’s disease (AD), and healthy control subjects (NC) was carried out in terms of the cortical localization of oscillatory EEG activity. ► As compared to NC, FTD had significantly reduced alpha generators in fronto-tem...

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Veröffentlicht in:Clinical neurophysiology 2011-09, Vol.122 (9), p.1718-1725
Hauptverfasser: Nishida, K, Yoshimura, M, Isotani, T, Yoshida, T, Kitaura, Y, Saito, A, Mii, H, Kato, M, Takekita, Y, Suwa, A, Morita, S, Kinoshita, T
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Sprache:eng
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Zusammenfassung:Research highlights ► A comparative study of frontotemporal dementia (FTD), Alzheimer’s disease (AD), and healthy control subjects (NC) was carried out in terms of the cortical localization of oscillatory EEG activity. ► As compared to NC, FTD had significantly reduced alpha generators in fronto-temporal cortices, while AD showed significantly stronger delta generators that included the frontal lobes. ► ROC curves demonstrate a moderate separation of FTD, AD, and NC groups.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2011.02.011