Endocytic sorting of transmembrane protein cargo

Highlights ► Recognition of sorting signals by clathrin adaptors is reviewed. ► New modes of adaptor-signal recognition have been discovered. ► Preference for poly-ubiquitination versus mono-ubiquitination has been explored structurally. ► New regulatory mechanisms have been elucidated.

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Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in cell biology 2011-08, Vol.23 (4), p.404-412
Hauptverfasser:	Kelly, Bernard T, Owen, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Clathrin - metabolism Clathrin-Coated Vesicles - metabolism Endocytosis Humans Internal Medicine Protein Transport Proteins - chemistry Proteins - metabolism Signal Transduction Transport Vesicles - metabolism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Highlights ► Recognition of sorting signals by clathrin adaptors is reviewed. ► New modes of adaptor-signal recognition have been discovered. ► Preference for poly-ubiquitination versus mono-ubiquitination has been explored structurally. ► New regulatory mechanisms have been elucidated.
ISSN:	0955-0674 1879-0410
DOI:	10.1016/j.ceb.2011.03.004