The Cat That Caught the Canary: What To Do with Single-Molecule Trapping

The Cat That Caught the Canary: What To Do with Single-Molecule Trapping

It has recently become possible to trap individual fluorescent biomolecules in aqueous solution by using real-time tracking and active feedback to suppress Brownian motion. We propose areas of investigation in which anti-Brownian electrokinetic (ABEL) trapping of single molecules is likely to lead t...

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Veröffentlicht in:ACS nano 2011-07, Vol.5 (7), p.5296-5299
Hauptverfasser: Cohen, Adam E, Fields, Alexander P
Format: Artikel
Sprache:eng
Schlagworte:
Brownian motion
Dynamic tests
Electrokinetics
Fluorescence
Microscopy, Fluorescence
Motion
Nanostructure
Nanostructures - chemistry
Real time
Surface Properties
Tracking
Trapping
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Zusammenfassung:It has recently become possible to trap individual fluorescent biomolecules in aqueous solution by using real-time tracking and active feedback to suppress Brownian motion. We propose areas of investigation in which anti-Brownian electrokinetic (ABEL) trapping of single molecules is likely to lead to significant new insights into biomolecular dynamics.
ISSN:1936-0851
1936-086X
DOI:10.1021/nn202313g