Automated regional wall motion abnormality detection by combining rest and stress cardiac MRI: Correlation with contrast-enhanced MRI

Purpose: To correlate an automated regional wall motion abnormality (RWMA) detection method based on combined rest and dobutamine‐stress cardiac MRI with the assessment of myocardial infarction from contrast‐enhanced MRI (CE‐MRI), and to demonstrate that adding stress data improves the detection of...

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Veröffentlicht in:Journal of magnetic resonance imaging 2011-08, Vol.34 (2), p.270-278
Hauptverfasser: Suinesiaputra, Avan, Frangi, Alejandro F., Kaandorp, Theodorus A.M., Lamb, Hildo J., Bax, Jeroen J., Reiber, Johan H.C., Lelieveldt, Boudewijn P.F.
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Sprache:eng
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Zusammenfassung:Purpose: To correlate an automated regional wall motion abnormality (RWMA) detection method based on combined rest and dobutamine‐stress cardiac MRI with the assessment of myocardial infarction from contrast‐enhanced MRI (CE‐MRI), and to demonstrate that adding stress data improves the detection of scar segments compared with rest data alone. Materials and Methods: An automated RWMA detection method was built based on a statistical model of normokinetic myocardium from 41 healthy volunteers. The method was adapted to detect changes in RWMA from rest to stress. Twelve patients with myocardial infarction were included in the experiment. The correlation with CE‐MRI was performed on two measurements: infarct transmurality and scar detection. Results: Compared with infarct transmurality, the probability of normokinetic motion decreased progressively as infarct transmurality increased. These probability values were 0.59 for non‐scar segments, for
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.22601