Principles for designing fluorescent sensors and reporters

Sensors and reporters are among the most exciting tools used in cell biology. Now, they are increasingly used in developmental biology and medicine because they allow us to spy on events in living cells and organisms, including humans, in real time and with high spatial resolution. Herein, we discus...

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Veröffentlicht in:Nature chemical biology 2011-07, Vol.7 (8), p.480-483
Hauptverfasser: Lemke, Edward A, Schultz, Carsten
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description Sensors and reporters are among the most exciting tools used in cell biology. Now, they are increasingly used in developmental biology and medicine because they allow us to spy on events in living cells and organisms, including humans, in real time and with high spatial resolution. Herein, we discuss multiple design options for fluorescent sensors and reporters as well as strategies to improve their properties and increase development.
doi_str_mv 10.1038/nchembio.620
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subjects 631/1647/1888/2249
631/1647/666
Biochemical Engineering
Biochemistry
Bioorganic Chemistry
Biosensing Techniques - methods
Cell Biology
Cell Physiological Phenomena
Cellular biology
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
commentary
Fluorescence
Humans
Indicators and Reagents
Sensors
title Principles for designing fluorescent sensors and reporters
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