A new link between pesticides and Parkinson's disease

A new link between pesticides and Parkinson's disease

Environmental factors are thought to be an important cause of Parkinson's disease. A new study shows that rats chronically treated with the mitochondrial inhibitor rotenone, a common pesticide, develop neuropathological and behavioral symptoms of Parkinsonism.

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Bibliographische Detailangaben
Veröffentlicht in:Nature neuroscience 2000-12, Vol.3 (12), p.1227-1228
Hauptverfasser: Giasson, Benoit I, Lee, Virginia M.-Y
Format: Artikel
Sprache:eng
Schlagworte:
Animal Genetics and Genomics
Animals
Behavioral Sciences
Biological Techniques
Biomedical and Life Sciences
Biomedicine
Control
Environmental Exposure - adverse effects
Health aspects
Humans
Lewy Bodies - metabolism
Lewy Bodies - pathology
Nerve Tissue Proteins - genetics
Nerve Tissue Proteins - metabolism
Neurobiology
Neurons
Neurosciences
news-and-views
Parkinson Disease - genetics
Parkinson Disease - metabolism
Parkinson Disease, Secondary - chemically induced
Parkinson's disease
Pesticides
Pesticides - toxicity
Physiological aspects
Risk factors
Rotenone - toxicity
Synucleins
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Beschreibung
Zusammenfassung:Environmental factors are thought to be an important cause of Parkinson's disease. A new study shows that rats chronically treated with the mitochondrial inhibitor rotenone, a common pesticide, develop neuropathological and behavioral symptoms of Parkinsonism.
ISSN:1097-6256
1546-1726
DOI:10.1038/81737