Dietary tryptophan restriction in rats triggers astrocyte cytoskeletal hypertrophy in hippocampus and amygdala

We have previously reported that dietary tryptophan (TRP) restriction in a rat crucial postnatal developmental stage induces depression-like behavior and alters dendritic spine density in CA1 pyramidal neurons and granule cells of the hippocampus. Due to astrocyte involvement in critical brain mecha...

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Veröffentlicht in:	Neuroscience letters 2009-02, Vol.450 (3), p.242-245
Hauptverfasser:	Zhang, Limei, Corona-Morales, Aleph A., Vega-González, Arturo, García-Estrada, Joaquín, Escobar, Alfonso
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala Amygdala - metabolism Amygdala - pathology Amygdala - physiopathology Animals Astrocyte activation Astrocytes - metabolism Astrocytes - pathology Biological and medical sciences Biomarkers - metabolism Brain - metabolism Brain - pathology Brain - physiopathology Cell Shape - physiology Cytoskeleton - metabolism Cytoskeleton - pathology Food, Formulated - adverse effects Fundamental and applied biological sciences. Psychology GFAP Glial Fibrillary Acidic Protein - metabolism Glial reactivity Gliosis - metabolism Gliosis - pathology Gliosis - physiopathology Hippocampus - metabolism Hippocampus - pathology Hippocampus - physiopathology Hypertrophy - metabolism Hypertrophy - pathology Hypertrophy - physiopathology Male Malnutrition - metabolism Malnutrition - pathology Malnutrition - physiopathology Rats Rats, Wistar Serotonin Serotonin - biosynthesis Serotonin - deficiency Tryptophan - deficiency Vertebrates: nervous system and sense organs
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