Synthesizing and binding dual-mode poly (lactic-co-glycolic acid) (PLGA) nanobubbles for cancer targeting and imaging

Abstract Accurate assessment of tumor boundaries and recognition of occult disease are important oncologic principles in cancer surgeries. However, existing imaging modalities are not optimized for intraoperative cancer imaging applications. We developed a nanobubble (NB) contrast agent for cancer t...

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Veröffentlicht in:	Biomaterials 2010-03, Vol.31 (7), p.1716-1722
Hauptverfasser:	Xu, Jeff S, Huang, Jiwei, Qin, Ruogu, Hinkle, George H, Povoski, Stephen P, Martin, Edward W, Xu, Ronald X
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Calibration Cancer targeting Cell Line, Tumor Dentistry Diagnostic Imaging - methods Dual-mode imaging Fluorescence Glycolates - chemical synthesis Glycolates - metabolism Humans Lactic Acid Nanobubbles Nanoparticles Nanostructures - chemistry Neoplasms - metabolism Polyglycolic Acid Spectrometry, Fluorescence Ultrasonics Ultrasound Xanthenes - metabolism
Online-Zugang:	Volltext
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