The association of ocular blood flow with haemorheological parameters in primary open‐angle and exfoliative glaucoma

. Purpose:  To evaluate the ocular blood flow velocities and haemorheological parameters in patients with primary open‐angle glaucoma (POAG), exfoliative glaucoma (XFG) and exfoliation syndrome (XFS) and to compare their results with those of healthy controls. Methods:  Twenty‐five patients with POA...

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Veröffentlicht in:Acta ophthalmologica (Oxford, England) England), 2011-08, Vol.89 (5), p.429-434
Hauptverfasser: Sekeroglu, Mehmet Ali, Irkec, Murat, Mocan, Mehmet Cem, Ileri, Esin, Dikmenoglu, Neslihan, Seringec, Nurten, Karaosmanoglu, Devrim, Orhan, Mehmet
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Sprache:eng
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Zusammenfassung:. Purpose:  To evaluate the ocular blood flow velocities and haemorheological parameters in patients with primary open‐angle glaucoma (POAG), exfoliative glaucoma (XFG) and exfoliation syndrome (XFS) and to compare their results with those of healthy controls. Methods:  Twenty‐five patients with POAG (group 1), 25 patients with XFG (group 2), 25 patients with XFS (group 3) and 25 healthy controls (group 4) were included in the study. Ocular blood flow velocities of ophthalmic artery (OA), central retinal artery (CRA) and short posterior ciliary arteries (SPCAs) were measured using colour Doppler imaging (CDI). Haemorheological parameters (erythrocyte elongation and aggregation index, aggregation amplitude, aggregation half‐life, plasma viscosity, haematocrit) were measured in venous blood samples of all patients. Results:  The peak systolic velocity (PSV) and end‐diastolic velocity (EDV) values were lower and resistive indices (RI) were higher for the OA, CRA and SPCA of glaucomatous (groups 1 and 2) patients compared with those of controls (group 4) (PSV: OA, 40.4 ± 11.3  versus 52.6 ± 12.8 cm/second, p 
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2009.01713.x