Kidney impairment in primary aldosteronism

Kidney impairment is noted in primary aldosteronism (PA), and probably initiated by glomerular hyperfiltration. A prospectively defined survey was conducted on 602 patients who were suspected of PA in the multiple-center Taiwan Primary Aldosteronism Investigation (TAIPAI) database. Estimated glomeru...

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Veröffentlicht in:	Clinica chimica acta 2011-07, Vol.412 (15-16), p.1319-1325
Hauptverfasser:	Wu, Vin-Cent, Yang, Shao-Yu, Lin, Jou-Wei, Cheng, Bor-Wen, Kuo, Chin-Chi, Tsai, Chia-Ti, Chu, Tzong-Shinn, Huang, Kuo-How, Wang, Shuo-Meng, Lin, Yen-Hung, Chiang, Chih-Kang, Chang, Hung-Wei, Lin, Chien-Yu, Lin, Lian-Yu, Chiu, Jainn-Shiun, Hu, Fu-Chang, Chueh, Shih-Chieh, Ho, Yi-Luwn, Liu, Kao-Lang, Lin, Shuei-Liong, Yen, Ruoh-Fang, Wu, Kwan-Dun
Format:	Artikel
Sprache:	eng
Schlagworte:	Glomerular Filtration Rate Humans Hyperaldosteronism - complications Hyperaldosteronism - diagnosis Hyperaldosteronism - drug therapy Hyperaldosteronism - physiopathology Hypertension - physiopathology Kidney Diseases - complications Kidney Diseases - physiopathology Kidney hyperfiltration Logistic Models Middle Aged Potassium - blood Primary aldosteronism Prospective Studies Renin Renin - blood Spironolactone - therapeutic use TAIPAI score
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Beschreibung
Zusammenfassung:	Kidney impairment is noted in primary aldosteronism (PA), and probably initiated by glomerular hyperfiltration. A prospectively defined survey was conducted on 602 patients who were suspected of PA in the multiple-center Taiwan Primary Aldosteronism Investigation (TAIPAI) database. Estimated glomerular filtration rate (eGFR) was calculated and followed up at 1yr after treatment. The diagnosis of PA was confirmed in 330 patients. Among them 17% of these patients had kidney impairment (eGFR
ISSN:	0009-8981 1873-3492
DOI:	10.1016/j.cca.2011.02.018