Economic burden of rotavirus disease in children under 5 years in Kazakhstan

Abstract Background We aimed to estimate the societal costs of rotavirus cases among children less than 5 years in Kazakhstan, an upper-middle income country in Central Asia. Methods Data on medical, non-medical and indirect costs were collected for 190 patients less than 5 years, hospitalized with severe diarrhea in 2009 in two pediatric hospitals. Data on resource use for moderate and mild diarrhea cases were obtained from published sources. A probabilistic sensitivity analysis was performed to explore uncertainty in cost estimates. Results Approximately 4,000 severe, 30,700 moderate, and 122,900 mild rotavirus cases were estimated annually in children