Pilot study of budesonide inhalant suspension irrigations for chronic eosinophilic sinusitis

[...]previous works have indicated that patients are able to recall symptoms of smell accurately.8 The lack of a control group makes it difficult to determine what role a placebo effect and the natural course of the disease may have played. A lack of significance in the pilot data was likely driven by the inclusion of patients with well controlled asthma; however, 3 of 4 subjects who did not have controlled disease at baseline did show improvement.\n In addition, asthma control was determined using National Institutes of Health guidelines.E2 Each visual analogue scale (VAS) question was converted to a numerical value (0-6) to allow statistical analysis of symptoms before and after treatment (maximum sinus score for 16 symptoms, 96; maximum asthma score for 6 symptoms, 36).