Automated GMP production of [11C]PR04.MZ via the captive solvent method and PET studies in non-human primates: A promising tracer for extrastriatal DAT imaging

Time-activity curves and distribution volumes (DVs) were derived for the putamen, the caudate nucleus, the nucleus accumbens, the midbrain and the cerebellum. Distribution volumes (DV) for various brain regions were obtained from Logan-plot analysis and binding potentials were calculated according t...

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Veröffentlicht in:	NeuroImage 2010-08, Vol.52 (S1), p.S117-S117
Hauptverfasser:	Riss, Patrick J., Hooker, Jacob M., Alexoff, David, Kim, Sung-Won, Hummerich, Rene, Ferrari, Valentina A., Schloss, Patrick, Fowler, Johanna S., Roesch, Frank, Aigbirhio, Franklin I.
Format:	Artikel
Sprache:	eng
Schlagworte:	[11C]PRO.4.MZ Automation BRAIN Dopamine human primates PET POSITRON COMPUTED TOMOGRAPHY PRIMATES PRODUCTION RADIOLOGY AND NUCLEAR MEDICINE radiotracer Rodents SOLVENTS
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